A51.45
ICD-10-CMThis code describes inflammation of the liver (hepatitis) that occurs as a manifestation of secondary syphilis. Secondary syphilis is a systemic stage of the infection characterized by widespread dissemination of the spirochete, Treponema pallidum, often presenting with mucocutaneous lesions and systemic symptoms, including hepatic involvement.
Assign this code when documentation explicitly states "secondary syphilitic hepatitis" or "hepatitis due to secondary syphilis." Supporting documentation should confirm a diagnosis of secondary syphilis and evidence of liver involvement, such as elevated liver enzymes or imaging findings consistent with hepatitis.
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