Disseminated herpesviral disease

This code represents a severe, widespread infection caused by a herpes simplex virus (HSV) that has spread beyond the initial site of infection to affect multiple organs or systems. It indicates a systemic involvement of HSV, often seen in immunocompromised individuals or neonates.

Apply this code when documentation clearly indicates a disseminated HSV infection, such as herpes encephalitis, hepatitis, pneumonitis, or widespread cutaneous involvement with systemic symptoms. Supporting documentation should specify the systemic nature of the herpesviral disease rather than localized manifestations.

• Differentiate from localized herpes simplex infections (e.g., B00.1, B00.2) which do not involve systemic spread.
• Always code any associated manifestations or complications, such as encephalitis (G05.1) or hepatitis (B10.0), as secondary diagnoses.
• Ensure the medical record explicitly states "disseminated" or describes multi-organ involvement due to HSV.