Human herpesvirus 6 infection

This code identifies an infection caused by Human Herpesvirus 6 (HHV-6), a common betaherpesvirus. HHV-6 is primarily known for causing roseola infantum (exanthem subitum) in young children, but can also lead to more severe manifestations in immunocompromised individuals, including encephalitis, pneumonitis, and bone marrow suppression.

Apply this code when documentation confirms an active HHV-6 infection, regardless of the specific clinical manifestation. This includes cases of roseola infantum, as well as other symptomatic presentations of HHV-6. Supporting documentation should include laboratory confirmation (e.g., PCR, serology) or a definitive clinical diagnosis by a physician.

• Do not use this code for latent or asymptomatic HHV-6 carriage; it is for active infection only.
• Consider additional codes for specific manifestations or complications of the HHV-6 infection (e.g., encephalitis, pneumonia).
• Differentiate from other herpesvirus infections (e.g., HSV, VZV, CMV) which have distinct codes.