Disseminated aspergillosis

This code signifies a severe, systemic fungal infection caused by Aspergillus species, where the infection has spread from the primary site to multiple non-contiguous organs or tissues throughout the body. It indicates a widespread and often life-threatening form of aspergillosis, distinct from localized or single-organ involvement.

Assign this code when medical record documentation explicitly states "disseminated aspergillosis" or describes Aspergillus infection affecting multiple distant organ systems (e.g., lungs, brain, kidneys, skin) in an immunocompromised patient. Supporting documentation will often include positive cultures from multiple sites, imaging evidence of widespread lesions, and pathology reports confirming Aspergillus in various tissues.

• Do not use for localized aspergillosis (e.g., aspergilloma, allergic bronchopulmonary aspergillosis) or single-organ invasive aspergillosis.
• Always code the underlying immunocompromised state (e.g., malignancy, HIV, transplant status) as a primary or secondary diagnosis, as it is often a predisposing factor.
• Specify the type of aspergillosis (e.g., Aspergillus fumigatus) if documented, using an additional code from B44.0-B44.6, if applicable and further specified.