Mesothelioma of pleura

This code identifies a primary malignant tumor originating from the mesothelial cells lining the pleura, the membrane surrounding the lungs and lining the chest cavity. This aggressive cancer is most commonly associated with asbestos exposure.

Assign this code when documentation explicitly states a diagnosis of mesothelioma specifically affecting the pleura. This diagnosis is typically confirmed through biopsy and histopathological examination.

• Do not use this code for secondary or metastatic pleural malignancies; this code is exclusively for primary mesothelioma of the pleura.
• Be mindful of the "Excludes1" note for C38.4 (other malignant neoplasm of pleura) to avoid incorrect co-coding.
• Ensure the medical record clearly specifies the pleura as the primary site of the mesothelioma.