D59.39
ICD-10-CMThis code represents hemolytic-uremic syndrome (HUS) that does not fit the criteria for typical (Shiga toxin-producing E. coli-associated) HUS or atypical HUS. It encompasses various less common forms of HUS, characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The underlying etiology is diverse and may include drug-induced, transplant-associated, or other secondary causes.
Use this code when documentation specifies HUS that is not clearly identified as typical (STEC-HUS) or atypical (aHUS). This includes cases where the cause is attributed to specific medications, organ transplantation, or other rare conditions leading to the HUS triad. Supporting documentation should clearly rule out STEC-HUS and aHUS, or explicitly state an alternative etiology.
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