Chronic acquired pure red cell aplasia

This code represents a chronic condition characterized by the selective absence or marked decrease of erythroid precursors in the bone marrow, leading to severe anemia. It is an acquired form, meaning it develops later in life rather than being congenital, and specifically affects red blood cell production while other blood cell lines remain normal.

Use this code for patients diagnosed with long-standing pure red cell aplasia that is not congenital or transient. Documentation should clearly indicate the chronicity of the condition and the selective erythroid aplasia, often supported by bone marrow biopsy findings and persistent anemia requiring treatment.

• Distinguish from transient erythroblastopenia of childhood or congenital forms of pure red cell aplasia.
• Code any underlying cause or associated conditions (e.g., thymoma, autoimmune disease) as additional diagnoses.
• Ensure documentation specifies "acquired" and "chronic" to support accurate code assignment.