Antineoplastic chemotherapy induced pancytopenia

This code signifies a reduction in all major blood cell lines (red blood cells, white blood cells, and platelets) caused by antineoplastic chemotherapy. It represents a severe, generalized bone marrow suppression resulting from cancer treatment.

Apply this code when documentation explicitly links pancytopenia to the administration of chemotherapy for cancer. This diagnosis requires evidence of decreased counts across erythrocytes, leukocytes, and thrombocytes, directly attributed to the cytotoxic effects of antineoplastic agents.

• Ensure documentation clearly states "pancytopenia" and specifies "antineoplastic chemotherapy induced."
• Do not use this code if only one or two cell lines are affected; use specific cytopenia codes instead.
• Distinguish from aplastic anemia due to chemotherapy (D61.1), which implies a more severe and often irreversible bone marrow failure.