Diabetes insipidus

This code represents a rare disorder characterized by excessive thirst (polydipsia) and the excretion of large amounts of dilute urine (polyuria) due to a deficiency in the production or release of antidiuretic hormone (ADH), also known as vasopressin, from the posterior pituitary gland. This deficiency prevents the kidneys from reabsorbing enough water, leading to dehydration and electrolyte imbalances.

Use this code when documentation specifies central or neurogenic diabetes insipidus, indicating a problem with ADH production or secretion. This diagnosis is typically supported by clinical findings of polyuria, polydipsia, and a water deprivation test confirming the inability to concentrate urine, along with imaging or lab results pointing to a pituitary or hypothalamic cause.

• Always differentiate between central diabetes insipidus and nephrogenic diabetes insipidus; the latter has a specific Excludes1 note.
• Ensure documentation clearly states the etiology as central or neurogenic to support this code.
• Consider sequencing this code as a primary diagnosis if it is the reason for the encounter, or as a secondary diagnosis if it is a co-morbidity affecting treatment.