Polyglandular hyperfunction

This code represents the overactivity of multiple endocrine glands, leading to an excess production of their respective hormones. It signifies a systemic endocrine imbalance affecting more than one glandular system, but not necessarily due to neoplastic processes.

Use this code when documentation clearly indicates hyperfunction of two or more distinct endocrine glands, such as concurrent hyperthyroidism and hyperparathyroidism, without a specified underlying neoplastic cause. Supporting documentation should detail the specific glands involved and evidence of their overactivity (e.g., elevated hormone levels, clinical signs and symptoms).

• Differentiate carefully from multiple endocrine neoplasia (MEN) syndromes, which are excluded.
• Ensure documentation specifies hyperfunction, not hypofunction or other endocrine disorders.
• Code any specific manifestations or underlying causes of the polyglandular hyperfunction, if known and documented, in addition to this code.