Leukoencephalopathy with calcifications and cysts

This code identifies a rare, progressive neurological disorder characterized by widespread white matter abnormalities in the brain, accompanied by the presence of calcifications and cystic lesions. It typically manifests with a range of neurological symptoms, including developmental delay, seizures, spasticity, and cognitive decline, often presenting in childhood.

Assign this code for patients diagnosed with leukoencephalopathy specifically documented to include both calcifications and cysts on neuroimaging studies (e.g., MRI, CT scan). Documentation should clearly indicate the presence of these distinct features to differentiate it from other forms of leukoencephalopathy.

• Ensure documentation explicitly states "calcifications" and "cysts" in conjunction with leukoencephalopathy; otherwise, a more general leukoencephalopathy code may be appropriate.
• Review imaging reports and physician notes carefully for the specific findings that support this diagnosis.
• Consider sequencing this code as the primary diagnosis when it is the main reason for the encounter or hospitalization.