I21.B
ICD-10-CMMyocardial infarction with coronary microvascular dysfunction
This code represents a myocardial infarction (heart attack) that is specifically attributed to dysfunction within the heart's smallest blood vessels (microvasculature), rather than a blockage in a major coronary artery. This type of MI occurs despite patent epicardial coronary arteries, indicating a problem at the microcirculatory level.
Use this code when documentation explicitly states a myocardial infarction due to coronary microvascular dysfunction, often following diagnostic evaluation ruling out epicardial coronary artery obstruction. This diagnosis is typically supported by findings from cardiac MRI, PET scans, or invasive coronary function testing demonstrating impaired microvascular flow.
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