Panlobular emphysema

This code identifies emphysema characterized by uniform destruction and enlargement of the airspaces distal to the terminal bronchioles, involving the entire acinus. It is often associated with alpha-1 antitrypsin deficiency, leading to widespread lung damage. This form of emphysema typically affects the lower lobes of the lungs.

Assign this code when documentation specifically states "panlobular emphysema" or "panacinar emphysema." This diagnosis is frequently made in patients with a confirmed or suspected genetic predisposition, such as alpha-1 antitrypsin deficiency. Supporting documentation often includes imaging reports (e.g., CT scan) describing diffuse emphysematous changes.

• Do not confuse with centrilobular emphysema, which is more common and typically associated with smoking.
• Always look for documentation of the specific type of emphysema; if not specified, a more general emphysema code may be appropriate.
• Consider co-coding with E88.01 (Alpha-1-antitrypsin deficiency) if documented as the underlying cause.