Toxic liver disease with cholestasis

This code signifies liver damage resulting from exposure to toxic substances, specifically characterized by impaired bile flow (cholestasis). This impairment leads to the accumulation of bile within the liver, causing jaundice, pruritus, and potential hepatocellular injury. The toxic agent can be a drug, chemical, or herbal supplement.

Apply this code when documentation clearly indicates liver dysfunction directly attributable to a toxic exposure, with evidence of cholestasis (e.g., elevated alkaline phosphatase, conjugated bilirubin, GGT). This is appropriate for cases of drug-induced cholestatic hepatitis or chemical-induced intrahepatic cholestasis. Ensure the causal link between the toxin and the liver injury is explicitly stated.

• Always identify the specific toxic agent responsible for the liver disease using an external cause code (T36-T65) in conjunction with this code.
• Differentiate from other forms of toxic liver disease without cholestasis (e.g., K71.1, K71.2) or non-toxic cholestasis (e.g., K76.89).
• Ensure documentation specifies "cholestasis" or clinical findings consistent with bile flow obstruction (e.g., jaundice, elevated conjugated bilirubin, pruritus) in the context of toxic exposure.