O74.4
ICD-10-CMThis code identifies an adverse systemic response to a local anesthetic agent administered during the peripartum period. This reaction is due to the toxic effects of the drug itself, rather than an allergic or hypersensitivity response. Manifestations can include central nervous system (CNS) toxicity (e.g., seizures, altered mental status) or cardiovascular toxicity (e.g., arrhythmias, hypotension).
Assign this code when documentation clearly indicates a toxic reaction to a local anesthetic (e.g., lidocaine, bupivacaine) administered for pain management during labor, delivery, or immediately postpartum. This includes epidural, spinal, or local infiltration anesthesia. Documentation should specify "toxic reaction" or "drug toxicity" rather than "allergic reaction" or "adverse effect, not otherwise specified."
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