Abnormal findings on neonatal screening for cystic fibrosis

This code signifies an initial positive or abnormal result from a newborn screening test for cystic fibrosis (CF). It indicates the presence of markers suggesting a potential diagnosis of CF, requiring further diagnostic evaluation. This is not a definitive diagnosis of CF itself, but rather an alert from the screening process.

Use this code when a newborn's initial screening test for cystic fibrosis, typically a blood spot test measuring immunoreactive trypsinogen (IRT), returns an abnormal or positive result. This code is appropriate when the infant is undergoing follow-up testing, such as a sweat chloride test or genetic analysis, to confirm or rule out CF. Documentation should clearly state "abnormal newborn screen for cystic fibrosis" or similar.

• Do not use this code for a confirmed diagnosis of cystic fibrosis; instead, use codes from category E84.
• This code is typically a primary diagnosis when the infant is being evaluated for the abnormal screen.
• Ensure documentation specifies "abnormal neonatal screening" to differentiate from diagnostic testing.