Kernicterus due to isoimmunization

This code identifies brain damage in a neonate resulting from severe unconjugated hyperbilirubinemia caused by maternal-fetal blood group incompatibility. It signifies the neurological sequelae of bilirubin encephalopathy, often presenting with symptoms like hypotonia, seizures, and hearing loss.

Apply this code when documentation explicitly states kernicterus in a newborn and links its etiology to isoimmunization (e.g., Rh or ABO incompatibility). Supporting documentation will include laboratory findings of severe hyperbilirubinemia, evidence of isoimmunization, and neurological signs consistent with bilirubin-induced brain injury.

• Always code the underlying cause of the hyperbilirubinemia (e.g., P55.- for hemolytic disease of newborn) in addition to this code.
• Do not use this code for hyperbilirubinemia without documented neurological damage.
• Ensure the medical record clearly distinguishes kernicterus from less severe forms of bilirubin encephalopathy.