Hepatomegaly with splenomegaly, not elsewhere classified

This code signifies the simultaneous enlargement of both the liver and the spleen, a condition often indicative of underlying systemic disease. It is used when the specific cause of this hepatosplenomegaly has not been definitively diagnosed or is not classifiable to a more specific ICD-10-CM code.

Apply this code when documentation clearly states "hepatosplenomegaly" or "enlarged liver and spleen" without a more specific etiology identified. This is appropriate for initial encounters or when the diagnostic workup for the underlying cause is still in progress.

• Do not use this code if a definitive diagnosis for the hepatosplenomegaly (e.g., cirrhosis, lymphoma, infectious mononucleosis) is documented; instead, code the specific condition.
• Always sequence this code after any definitive underlying condition if known and documented.
• Query the provider if "hepatosplenomegaly" is noted but the cause is unclear, to determine if a more specific diagnosis can be assigned.