Cachexia

This code signifies a state of severe wasting and malnutrition, characterized by significant involuntary weight loss, muscle atrophy, and weakness. It is a complex metabolic syndrome often associated with chronic diseases, leading to a profound decline in physical function.

Use this code when documentation explicitly states "cachexia" without specifying an underlying cause or when the underlying condition is unknown. This code is appropriate when the provider identifies the patient's severe wasting as a distinct clinical entity requiring management.

• Do not use this code if the documentation specifies cachexia due to a known underlying condition; instead, code the underlying condition and the specific cachexia code (E88.A).
• Distinguish from simple abnormal weight loss (R63.4), which lacks the systemic inflammatory and metabolic derangements of cachexia.
• Ensure the medical record clearly supports the diagnosis of cachexia, not just general malnutrition or weight loss.