R76.12
ICD-10-CMNonspecific reaction to cell mediated immunity measurement of gamma interferon antigen response without active tuberculosis
This code indicates an abnormal or indeterminate result from an interferon-gamma release assay (IGRA), such as a Quantiferon-TB Gold or T-Spot.TB test, in a patient who does not have active tuberculosis. It signifies a positive or equivocal immune response to Mycobacterium tuberculosis antigens, suggesting latent infection or prior exposure, but without clinical evidence of active disease.
Use this code when an IGRA test returns a positive or indeterminate result, and the provider explicitly documents that there is no active tuberculosis. This typically occurs during screening for latent TB infection in high-risk individuals, such as healthcare workers, immunocompromised patients, or contacts of active TB cases, when subsequent workup rules out active disease.
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