Adverse effect of other estrogens and progestogens, sequela

This code signifies a long-term or residual condition resulting from a past adverse reaction to estrogen or progestogen medications, excluding oral contraceptives. It indicates that the initial adverse effect has resolved, but a lasting health problem remains due to that prior event.

Apply this code when documenting a chronic or permanent health issue that is a direct consequence of a previous adverse effect from non-contraceptive estrogen or progestogen therapy. Examples include persistent organ damage, chronic pain, or metabolic disturbances directly attributable to the past drug reaction.

• Always sequence this code after the code for the specific sequela (e.g., chronic liver disease, osteoporosis).
• Ensure documentation clearly links the current condition to a past adverse effect of the specified drug class.
• Do not use for acute adverse effects; those require an initial or subsequent encounter code.