Adverse effect of other opioids, subsequent encounter

This code signifies a patient experiencing an unintended and undesirable reaction to an opioid medication other than heroin, natural opium alkaloids, or methadone. This adverse effect occurs after the initial treatment phase for the condition that caused the adverse effect.

Apply this code when documenting follow-up care for a patient who previously experienced an adverse effect from an opioid medication (e.g., oxycodone, fentanyl, hydrocodone) and is now being seen for ongoing management or monitoring of that reaction. This includes situations where the patient is being treated for symptoms like severe constipation, nausea, or respiratory depression that developed as a side effect of the opioid.

• Always use in conjunction with a code identifying the specific adverse effect (e.g., R11.2 for nausea and vomiting).
• Ensure the documentation clearly indicates that the encounter is for the sequelae or ongoing management of the adverse effect, not the initial treatment.
• Distinguish from poisoning (T40.2X1-T40.2X4) and underdosing (T40.2X6-).