Heart transplant rejection

This diagnosis code signifies the body's immune system attacking a transplanted heart, leading to organ dysfunction. It encompasses various forms of rejection, including hyperacute, acute cellular, and antibody-mediated rejection, which can manifest at different times post-transplant.

Apply this code when a patient with a history of heart transplantation presents with signs and symptoms indicative of their immune system rejecting the allograft. This includes findings from biopsies, imaging, and laboratory tests confirming rejection, regardless of the specific type or severity.

• Always code the specific type of heart transplant rejection when known (e.g., acute, chronic) if a more granular code is available.
• Ensure supporting documentation clearly states "rejection" of the heart transplant, not just "failure" or "complication."
• Consider co-coding with codes for associated symptoms or complications of the rejection, such as heart failure or arrhythmias.