Cytomegaloviral disease

This code represents a range of clinical manifestations caused by infection with the cytomegalovirus (CMV). CMV disease can affect various organ systems, including the lungs, gastrointestinal tract, central nervous system, and retina, particularly in immunocompromised individuals. It signifies active, symptomatic infection rather than latent or asymptomatic carriage.

Use this code when documentation clearly indicates active cytomegaloviral disease, such as CMV pneumonitis, retinitis, colitis, or encephalitis. This code is appropriate for both congenital and acquired CMV infections that are causing symptomatic illness. Supporting documentation should include laboratory confirmation of CMV infection (e.g., positive PCR, viral culture) alongside clinical signs and symptoms.

• Do not use this code for asymptomatic CMV infection or positive serology without active disease.
• Always code the specific manifestation of CMV disease (e.g., CMV pneumonia, CMV retinitis) first, if a more specific ICD-9 code exists, and then use this code as a secondary diagnosis if applicable to further specify the viral etiology.
• Consider additional codes for associated conditions, such as immunosuppression (e.g., HIV, organ transplant status), which often predispose patients to CMV disease.