Malignant neoplasm of isthmus

This code signifies a cancerous tumor originating in the isthmus of the uterus. The isthmus is the narrow, lower segment of the uterus, connecting the body of the uterus to the cervix. This diagnosis indicates a primary malignancy at this specific anatomical site.

Assign this code when documentation clearly specifies a primary malignant neoplasm located in the uterine isthmus. This typically follows pathological confirmation from biopsy or surgical resection. Use this code for initial encounters and subsequent treatment of this specific cancer.

• Differentiate carefully from malignancies of the uterine corpus (e.g., endometrium) or cervix, as these have distinct codes.
• Ensure the pathology report explicitly identifies the isthmus as the primary site of the malignancy.
• Consider sequencing rules for primary versus secondary malignancies and any associated complications or treatments.