Polycythemia vera

This code represents a chronic myeloproliferative neoplasm characterized by the overproduction of all three myeloid cell lines, predominantly red blood cells. It results in increased blood viscosity, leading to symptoms such as headache, dizziness, visual disturbances, and an increased risk of thrombosis and hemorrhage.

Use this code for documented cases of primary polycythemia, where the bone marrow produces too many red blood cells independently of erythropoietin stimulation. Documentation should confirm a diagnosis of polycythemia vera, often supported by elevated hemoglobin/hematocrit, increased red cell mass, and genetic testing (e.g., JAK2 mutation).

• Differentiate from secondary polycythemia (e.g., due to hypoxia), which has different underlying causes and coding.
• Ensure documentation specifies "vera" to distinguish from other forms of polycythemia.
• Consider sequencing if complications (e.g., thrombosis, myelofibrosis) are also present and being treated.