Poisoning by antineoplastic and immunosuppressive drugs

This code signifies an adverse reaction or overdose resulting from antineoplastic agents (chemotherapy drugs) or immunosuppressants. It covers both accidental and intentional poisonings, as well as adverse effects from therapeutic use. The patient experiences toxic effects due to the drug's presence in their system.

Apply this code when documentation clearly indicates a patient's signs and symptoms are directly attributable to an overdose or toxic effect of a chemotherapy drug or an immunosuppressant. This includes situations like accidental ingestion, incorrect dosage administration, or an individual's heightened sensitivity leading to toxicity. Supporting documentation would include physician notes detailing drug exposure, symptoms, and the causal link.

• Always identify the specific drug involved and its intent (e.g., accidental, intentional self-harm, adverse effect of proper use) using an E-code.
• Sequence this code as the principal diagnosis when the poisoning is the primary reason for the encounter.
• Do not confuse with adverse effects of drugs properly administered and taken, which would typically be coded with an E-code and a manifestation code, unless the documentation specifies a poisoning.