Toxic shock syndrome

This code represents a severe, acute, and potentially life-threatening systemic illness caused by bacterial toxins, most commonly from Staphylococcus aureus or Streptococcus pyogenes. It is characterized by a rapid onset of fever, hypotension, rash, and multi-organ dysfunction.

Use this code when documentation clearly indicates a diagnosis of toxic shock syndrome, often associated with tampon use, surgical wounds, or other localized infections. Supporting documentation should detail the clinical presentation consistent with TSS, including systemic inflammatory response and organ involvement.

• Do not use this code for endotoxic shock not otherwise specified (NOS) or general sepsis, as these are excluded conditions.
• Always review the medical record for the specific bacterial etiology if documented, as additional codes for the infectious agent may be warranted.
• Ensure the documentation differentiates between toxic shock syndrome and other forms of shock or severe infection.