Asymptomatic neurosyphilis

This code represents a stage of syphilis where the central nervous system (CNS) is affected, but the patient exhibits no overt neurological symptoms. It is typically identified through abnormal cerebrospinal fluid (CSF) findings in an individual with a history of syphilis infection. This condition indicates active treponemal infection within the CNS without clinical manifestation.

Use this code when documentation confirms neurosyphilis based on CSF abnormalities (e.g., elevated CSF white blood cell count, elevated CSF protein, positive CSF VDRL or FTA-ABS) in a patient who is asymptomatic. This diagnosis often arises during the workup of syphilis, particularly in later stages, or in individuals with HIV co-infection. Documentation must explicitly state "asymptomatic neurosyphilis" or provide clear evidence of CNS involvement without neurological signs.

• Do not use this code if the patient presents with any neurological symptoms; instead, select a more specific code for symptomatic neurosyphilis.
• Ensure documentation clearly distinguishes between asymptomatic neurosyphilis and other forms of latent syphilis without CNS involvement.
• Always code the underlying syphilis infection (e.g., A51.x, A52.x) first, followed by any associated manifestations.