Asymptomatic neurosyphilis

This code represents neurosyphilis that is present without any overt neurological signs or symptoms. It indicates central nervous system involvement by Treponema pallidum in an individual who is clinically asymptomatic. Diagnosis is typically made through cerebrospinal fluid (CSF) abnormalities, such as elevated protein, pleocytosis, or a positive CSF-VDRL.

Use this code when documentation confirms neurosyphilis based on CSF findings, but the patient exhibits no neurological complaints or deficits. This often occurs during the workup of latent syphilis or in patients with HIV co-infection. Documentation should clearly state "asymptomatic neurosyphilis" or describe CSF findings consistent with neurosyphilis in an asymptomatic patient.

• Do not use this code if the patient presents with any neurological symptoms; instead, select a more specific code for symptomatic neurosyphilis.
• Always sequence this code after the underlying syphilis infection (e.g., late latent syphilis).
• Ensure CSF laboratory results supporting the diagnosis are clearly documented in the medical record.