Cutaneous cryptococcosis

This code represents a fungal infection of the skin caused by Cryptococcus neoformans or Cryptococcus gattii. It can manifest as papules, nodules, ulcers, or cellulitis, often in immunocompromised individuals but also in immunocompetent hosts.

Use this code when documentation specifies cryptococcal infection localized to the skin, without evidence of systemic involvement. Supporting documentation would include pathology reports confirming Cryptococcus in skin biopsies or positive fungal cultures from cutaneous lesions.

• Always code the underlying systemic cryptococcosis (B45.-) first if the cutaneous manifestation is secondary to disseminated disease.
• Distinguish from other fungal skin infections; ensure documentation specifically identifies Cryptococcus.
• Look for documentation of immunocompromised status (e.g., HIV, organ transplant) as this often co-occurs, and code accordingly.