Disseminated cryptococcosis

This code represents a severe, widespread infection caused by the fungus Cryptococcus neoformans or Cryptococcus gattii. Disseminated cryptococcosis indicates that the infection has spread beyond the primary site, commonly affecting the central nervous system (meningitis), lungs, skin, and other organs. It is particularly prevalent in immunocompromised individuals.

Use this code when documentation confirms a systemic cryptococcal infection involving multiple body sites. This diagnosis is typically supported by positive fungal cultures from various sterile sites (e.g., CSF, blood), histopathology demonstrating cryptococcal organisms in multiple tissues, or serological evidence of widespread disease.

• Always code the specific manifestations of disseminated cryptococcosis (e.g., cryptococcal meningitis G02.1, cryptococcal pneumonia B45.1) as secondary diagnoses.
• Ensure documentation clearly states "disseminated" or indicates involvement of multiple non-contiguous sites.
• Consider the patient's immunocompromised status (e.g., HIV infection B20) as a co-morbidity, as it often influences treatment and prognosis.