Chronic lymphocytic leukemia of B-cell type in relapse

This code signifies a B-cell chronic lymphocytic leukemia (CLL) that was previously treated and has now recurred or worsened after a period of remission. It indicates the disease is no longer in a controlled state and requires further intervention.

Apply this code when documentation explicitly states B-cell CLL is in relapse, meaning the disease has returned or progressed after a period of improvement. This is typically supported by physician notes detailing disease progression, new or worsening symptoms, and/or laboratory findings indicating increased leukemic cell burden.

• Ensure documentation clearly specifies "B-cell type" and "in relapse" for accurate coding.
• Distinguish from "not having achieved remission" or "in remission" which would use different codes.
• Always sequence this code as the primary diagnosis when it is the reason for the encounter.