Increased secretion of glucagon

This code signifies an abnormally elevated level of glucagon, a hormone produced by the pancreas that raises blood glucose. This hyperglucagonemia can lead to hyperglycemia and is often associated with conditions like glucagonoma or severe stress.

Apply this code when documentation explicitly states "increased secretion of glucagon," "hyperglucagonemia," or "elevated glucagon levels" as a primary or secondary diagnosis. This is typically supported by laboratory findings showing high serum glucagon.

• Do not use this code for general hyperglycemia without specific documentation of increased glucagon secretion.
• Consider sequencing this code after the underlying cause of the hyperglucagonemia, if known (e.g., C25.4 for malignant neoplasm of islet cells).
• Ensure the medical record clearly distinguishes between elevated glucagon and other endocrine disorders affecting glucose metabolism.