Increased secretion of gastrin

This code represents an abnormally elevated level of gastrin hormone in the bloodstream. Gastrin is primarily produced by G cells in the stomach and duodenum, stimulating gastric acid secretion. Increased gastrin can lead to various gastrointestinal issues, including peptic ulcers.

Use this code when laboratory tests confirm hypergastrinemia, often in the workup for recurrent or severe peptic ulcer disease, Zollinger-Ellison syndrome, or pernicious anemia. Documentation should clearly state "increased gastrin secretion," "hypergastrinemia," or a specific gastrin level exceeding normal reference ranges.

• Do not use this code for conditions that cause secondary hypergastrinemia unless the elevated gastrin is the primary focus of the encounter.
• Consider sequencing this code after the definitive diagnosis (e.g., Zollinger-Ellison syndrome, peptic ulcer) if the hypergastrinemia is a manifestation of that condition.
• Ensure documentation specifies "increased" or "elevated" gastrin, as opposed to normal or decreased levels.