Gilbert syndrome

This code represents Gilbert syndrome, a common, benign, inherited liver condition characterized by intermittent unconjugated hyperbilirubinemia. It results from a reduced activity of the enzyme UDP-glucuronosyltransferase (UGT1A1), which is responsible for conjugating bilirubin in the liver. Individuals with Gilbert syndrome typically have no other signs of liver disease.

Use this code when documentation confirms a diagnosis of Gilbert syndrome, often identified incidentally during routine blood tests showing elevated unconjugated bilirubin in an otherwise healthy individual. Supporting documentation typically includes laboratory findings of elevated unconjugated bilirubin and a physician's diagnostic statement ruling out other causes of hyperbilirubinemia.

• Do not code for transient or unexplained hyperbilirubinemia without a definitive diagnosis of Gilbert syndrome.
• Ensure the documentation specifies "unconjugated" hyperbilirubinemia, as other forms may indicate different underlying conditions.
• This code is typically a primary diagnosis as it is a chronic, inherited condition.