Multi-system degeneration of the autonomic nervous system

This diagnosis code signifies a progressive neurological disorder characterized by widespread dysfunction of the autonomic nervous system, affecting multiple organ systems. It encompasses conditions like multiple system atrophy (MSA), where the body's involuntary functions, such as blood pressure, heart rate, digestion, and bladder control, are severely impaired due to neurodegeneration.

This code is appropriate for documenting a definitive diagnosis of multi-system degeneration of the autonomic nervous system, often after extensive neurological evaluation. Documentation should clearly indicate widespread autonomic failure impacting various systems, distinguishing it from more localized or secondary autonomic neuropathies.

• Ensure documentation explicitly states "multi-system degeneration" or a specific diagnosis like "multiple system atrophy" (MSA) to support this code.
• Do not code this with I95.1 (orthostatic hypotension NOS) as per the Excludes1 note; if orthostatic hypotension is a symptom of the multi-system degeneration, the degeneration code is primary.
• Consider additional codes for specific manifestations or complications of the autonomic dysfunction, such as urinary incontinence (N39.3) or dysphagia (R13.19), if documented.