SIRS of non-infectious origin w acute organ dysfunction

This code signifies a severe, generalized inflammatory response throughout the body that is not caused by an infection, but rather by other insults such as trauma, pancreatitis, or burns. Crucially, this systemic inflammation is accompanied by evidence of acute organ damage or failure, such as acute kidney injury, respiratory failure, or liver dysfunction. It represents a critical and life-threatening condition requiring intensive medical management.

Apply this code when documentation clearly indicates SIRS criteria are met (e.g., abnormal temperature, heart rate, respiratory rate, WBC count) and the physician explicitly states a non-infectious etiology. Furthermore, there must be documented evidence of new or worsening organ dysfunction directly attributable to the SIRS, such as acute renal failure, acute respiratory distress syndrome (ARDS), or disseminated intravascular coagulation (DIC).

• Ensure the physician's documentation explicitly rules out an infectious cause for the SIRS.
• Always code the underlying non-infectious condition (e.g., severe pancreatitis, extensive burns) first, followed by this code.
• Do not use this code if the organ dysfunction is chronic or pre-existing and not acutely exacerbated by the SIRS.