Hormone recept neg w hmn epdrml grth fctr recept 2 neg stat

This code signifies a specific tumor characteristic in breast cancer, indicating that the cancer cells do not express hormone receptors (estrogen or progesterone) and also lack overexpression of the HER2 protein. This particular molecular subtype is often referred to as "triple-negative" breast cancer.

Use this code when documentation explicitly states that a breast cancer tumor is both hormone receptor negative and HER2 negative, typically confirmed through immunohistochemistry (IHC) and/or FISH testing. This status is crucial for guiding treatment decisions, as these tumors do not respond to hormone therapy or HER2-targeted therapies.

• Ensure documentation clearly specifies both hormone receptor negativity and HER2 negativity.
• Do not use this code if only one of the statuses (e.g., only HER2 negative) is documented.
• This code is typically used as a secondary diagnosis to provide further specificity about the malignant neoplasm.